Kambo
A secretion from an Amazonian tree frog, applied to the skin. It is not a psychedelic, and it asks more of the body than anything else described here.
What it is
Kambo is the waxy secretion of Phyllomedusa bicolor, the giant monkey frog of the western Amazon. It is not a psychedelic. There is no hallucinogenic effect, and anyone arriving at it expecting one has misunderstood what it does.
The secretion is applied to small burns made on the skin, so it enters through the lymphatic system rather than the stomach. It contains peptides that act fast and hard. Flushing, a racing heart, swelling of the face and heavy vomiting are the ordinary response, not the sign of something going wrong, and they usually run their course in under an hour.
Cultural context
Several Indigenous peoples of the western Amazon use kambo, among them the Matsés, Katukina and Yawanawá. Accounts of its purpose differ by community: preparation before hunting, treatment for particular illnesses, and clearing what is sometimes translated as bad luck or panema.
It moved out of the Amazon comparatively recently. What is sold in North American and European wellness settings is not the same thing as the practice it borrows from, and it is worth being clear-eyed about which one is on offer.
Risks worth knowing
This is the page where the risks are the main thing to say.
Kambo is not a controlled substance in the United States. That says nothing about whether it is safe and a great deal about how little oversight exists. Deaths have been reported, and serious harm more often than that.
- Practitioners commonly instruct people to drink large volumes of water beforehand. Drinking too much too fast causes hyponatremia, which is dangerous on its own and has been implicated in kambo deaths.
- Cases of severe liver injury have been documented in the medical literature.
- Heart conditions, epilepsy, pregnancy and a range of prescription medications are contraindications.
- There is no licensing body, no training standard and no register. A practitioner's credentials cannot be checked against anything.
This page is a description, not a recommendation and not a guide. It deliberately contains no information about sourcing, preparation or dosing.
At a glance
- Also known as
- Sapo, vacina do sapo
- Source
- Secretion of Phyllomedusa bicolor, the giant monkey frog
- Origin
- Western Amazon: Brazil, Peru and neighbouring regions
- Not a psychedelic
- No hallucinogenic effect, despite being widely mistaken for one
- How it is used
- Applied to small burns made on the skin
- Legal status
- Not a controlled substance in the United States, and not regulated either
Also in plant medicine
-
An Amazonian brew with centuries of ceremonial use, and a set of medication interactions that make preparation genuinely consequential.
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The most familiar plant on this list, the most legally settled in Michigan, and still the least consistently understood.
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The fungus at the centre of most current research and most current legislation, in Michigan and elsewhere.